The William Blake Collection consists of more than 200 titles of which the majority are facsimiles of Blake's works or privately-printed reprints and editions containing facsimiles of the illustrations. The collection also forms part of a larger collection devoted to joint painter-illustrator-author books that include followers of Blake, e.g. Palmer & Calvert, William Morris, Eric Gill, and David Jones.

One of the highlights of the William Blake Collection is the 1951 Trianon Press edition of William Blake's Jerusalem.

The Rosa Breithaupt Clark Architectural Collection is the result of an endowment made by Herbert Spencer Clark in 1982 in memory of his late wife, Rosa Breithaupt Hewetson Clark, formerly of Kitchener. Included in purchases made through this endowment are exemplary treatises from the sixteenth to the twentieth century supportive of the School of Architecture's cultural history emphasis.

Awards made in 1987 and 1990 by the Social Sciences and Humanities Research Council (SSHRC) of Canada under their programme supporting the development of specialized research programmes enabled the collections to grow significantly. The first grant was dedicated to the purchase of landmark titles in the history and theory of architecture. Since the discourse of architecture ultimately looks back to the Roman writer, Vitruvius, it was appropriate that the first acquisition using these funds was a rare edition of a Vitruvian treatise printed in 1536.

The second of the SSHRC grants was awarded in 1990 specifically to support the collection in an area of critical importance: architectural developments in Northern Europe and on the North American frontier which have a profound effect on architectural theory and urban development in Canada.

A third award made by SSHRC allowed the Library to purchase The Dictionary of Architecture issued by the Architectural Publication Society (1853-1892), described as a monument to nineteenth-century scholarship.

Materials related to Reverend Alfred Henry Tyrer’s books and publications on birth control, sex education, and marriage life.

Includes pamphlets and order forms for Tyrer’s books Where did we come from, mother dear? (Marriage Welfare Bureau, 1939) and Sex, marriage and birth control (Marriage Welfare Bureau, 1936), and ephemera related to the books and the Marriage Welfare Bureau.

Also contains booklet Marriage welfare : some facts about birth-control by Reverend Alfred Henry Tyrer which acted as promotional material for the book Sex, marriage and birth control. Booklet includes sections: Birth-control, the population problem, definition of birth-control, birth control and war, mothers who die in child-birth, infant mortality, birth control vs. infanticide, birth-control vs. abortions, birth-control vs. degeneracy and disease, birth-control vs. prostitution, economics and birth-control, divorce, religion and birth-control, the present status of birth-control, a prairie marriage.

Materials were enclosed in an envelope sent from Ontario on July 10, 1941, and with a letter addressed to Steve E. Chorney from Ranfurly (Alberta) acting as an introduction to the publications and explaining their importance.

The Indigenous publications collection is a selection of published holdings held by Special Collections & Archives related to Indigenous peoples in Canada and abroad. with a primary focus on First Nations, Inuit, Métis communities. The collection consist of of books, periodicals, zines, and other published materials, produced by, about, and in the language(s) of various Indigenous peoples and communities.

Titles in this collection are varied in topic and will be of interest to those interested in grassroots activism, self-determination governance, land rights and stewardship, community building, and settler and religious colonialism.

The Grand River Conservation Authority Library was donated in 2005, accompanying the archival records of the Authority and its predecessors.

The Library was maintained at the GRCA headquarters for reference and research use and consists of works by and about the GRCA, including both internal and external reports and studies, periodicals, and monographs.

Unpublished library items are described as part of the GRCA archives while published items are catalogued as print material and are listed in the library catalogue.

The British Women's Periodicals Collection is made up of some 35,000 issues of British women's magazines published from 1893 to 1977. The majority of titles were published by the Amalgamated Press and publishers which it absorbed, and many copies are, in fact, copies from the publishers' own archives. Most titles in the collection are very rare.

Because these magazines were aimed at a mass market audience, the British Women's Periodicals Collection offers a unique opportunity to examine the interests and concerns of British women during the time period covered. The collection's content is primarily "popular" fiction written for a female audience, but magazines for children and youth are also well represented. Cooking, crafts, advice columns, fashion, health, and inspirational topics are also featured. Of particular interest are the advertisements, which illustrate contemporary attitudes in a vivid manner.

A collection of seven zines created by Jenna Rose Sands on topics including cultural appropriation, residential schools, missing and murdered Indigenous women and girls, Pow Wow etiquette and the 60s scoop. Much of the artwork is hand-drawn and includes collage work.