The William Blake Collection consists of more than 200 titles of which the majority are facsimiles of Blake's works or privately-printed reprints and editions containing facsimiles of the illustrations. The collection also forms part of a larger collection devoted to joint painter-illustrator-author books that include followers of Blake, e.g. Palmer & Calvert, William Morris, Eric Gill, and David Jones.

One of the highlights of the William Blake Collection is the 1951 Trianon Press edition of William Blake's Jerusalem.